…did not meet the equivalence limits (0.8, 1.25). Viral suppression, a key secondary clinical endpoint, was maintained in all HIV-positive subjects throughout the IM phase and the overall study. Each…
…drug discovery, from AI to £D deep-learning research to biologics. In the second article, we explore a groundbreaking ‘immuno-ablative’ neo- adjuvant immunotherapy clinical trial that Memorial Sloan Kettering Cancer Center…
A new free service will offer insights in under ten days to sponsors conducting clinical trials, identifying potential ‘zombie trials’ and providing actionable recommendations for failing trials. The Health Check…
…have joined forces to create PACE (Pathways to Antimicrobial Clinical Efficacy), a £30 ($36) million initiative supporting early-stage innovation against AMR. PACE will select, invest in and support projects that…
…CLEC-2, FcɣRIIA and PEAR1). The nanobodies can be used to develop validated clinical assays for testing patients with platelet disorders such as bleeding or thrombosis, and as research tools to…
…an early clinical trial, researchers showed that blocking the messages cancer uses to hijack white blood cells can re-sensitise a subset of advanced prostate cancers to treatment – shrinking tumours…
…categorising patients for clinical studies, or an alternative to PET brain imaging. The company says it will undertake a larger study in which an independent laboratory will be used to…
…demonstrating positive early results or entering clinical trials for the first time. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts….
…ranges from 5.9 to 15.4 months. In May 2015, the Department of Interventional Oncology of Renji Hospital in Shanghai collaborated with CARsgen Therapeutics to initiate the first clinical study with…
…critical aspects of clinical trial design and leveraging regulatory pathways, in addition to outlining the differences between fast track, break through therapy, priority review regulatory designations and accelerated approval pathways….
…Parkinson’s, sarcopenia and long Covid demonstrating positive early results or entering clinical trials for the first time. The top stories: Non-viral gene therapy shows early efficacy in lung cancer Positive…
…2024 and will look at a series of measures, including exercise tolerability. Professor David Strain, the clinical lead based at the University of Exeter Medical School, said: “Inflammation in the…
…advanced therapeutics into human clinical trials for haemophilia, Duchenne muscular dystrophy, giant axonal neuropathy, Pompe disease and heart failure. He holds more than 200 patents related to AAV technology. He…
