News round-up for 30 October – 3 November by DDW Editor Reece Armstrong My news highlights this week feature a variety of exciting clinical trial results and launches that are…
Phase II interim data for psilocybin analog CYB003 in major depressive disorder (MDD) showed rapid, robust, and clinically significant reduction of depression symptoms. Of the trial participants, 53.3% responded and…
Initial data from an ongoing Phase I/II study of HPK1 inhibitor NDI-101150 show clinical benefit in three patients with solid tumours, including one complete response in a patient with renal…
…mutations. Datopotamab deruxtecan, Daiichi Sankyo and AstraZeneca The companies shared results from multiple trials of their TROP2 directed DXd antibody drug conjugate (ADC) datopotamab deruxtecan (Dato-DXd). BEGONIA Phase Ib/II trial,…
…screening Fine-tuning function by optimizing multispecific formats Using pre-clinical biomarkers with clinical relevance Register for free to secure your place or to receive your exclusive download link after the event….
…all entering early in-human clinical trials to treat a range of diseases. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts….
…earlier FTI drug candidates. Kura has promising preclinical data supporting the rationale for combining KO-2806 with distinct classes of targeted therapies, including tyrosine kinase inhibitors, KRASG12C inhibitors and KRASG12D inhibitors….
…autotaxin inhibitor and arenaviral vaccine, all entering early in-human clinical trials to treat a range of diseases. The top stories: Natural killer cell therapy shows powerful anti-tumour activity Gamida Cell…
…levels in a preclinical setting. A Phase I clinical trial to evaluate the safety and tolerability of HB‑400 in humans is ongoing. Gilead is solely responsible for continued development and…
…organisations, ICON is partnering with the US Biomedical Advanced Research and Development Authority on a clinical trial of next-generation Covid-19 vaccine candidates. Joseph R Peterson, PhD, CTO & Co-founder of…
…and even clinical data. It constructs a holistic and integrated vision, enabling true understanding of complex biological systems. Consolidating comprehensive metadata from various databases, bringing molecular and functional information, interaction…
…data from Phase I clinical trials through Fosun Pharma, which is now progressing FS-1502 (IKS014) through Phase II and Phase III trials in China. The study is designed to evaluate…
…in vivo models and from human clinical samples support this important finding. These findings pave the way for clinical studies combining autotaxin inhibitors with TGF-β pathway inhibitors, addressing the fibrotic…
…of the tumour microenvironment. Additionally, the publication includes clinical data from 19 non-Hodgkin lymphoma patients who received the fresh formulation of GDA-201 in a Phase I study conducted at the…
…given by Dr Qasim Ahmad, Chief Medical Officer of IO Biotech, a Clinical Oncologist with two decades of strategic clinical development, medical affairs, and marketing authorisation expertise. Dr Ahmad will…
