Leucid Bio has been granted clinical trial authorisation by the UK Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase I/II clinical trial evaluating autologous NKG2D-targeted CAR-T cell…
…10 CD20 CAR-T demonstrated on-target activity resulting in durable B-cell aplasia In three animals treated at the planned clinical dose – and without preconditioning chemotherapy – peak CD20 CAR+ cells…
…mutational events can be traced by looking at their ‘mutational signature’. The researchers found a close match between the signature seen in these mutational events and the signature in clinical…
A considerable roadblock in the successful triaging of new therapeutics for liver and metabolic related diseases is the reliability and effectiveness of pre-clinical disease models. Methods employing animal models may…
…also reported on vaccine trials for a number of other conditions, including Nipah virus, rabies and lung cancer. You can listen below, or find The Drug Discovery World Podcast on…
Enrolment in a Phase I trial of a new investigational universal influenza vaccine candidate has begun at the National Institutes of Health’s Clinical Center in Bethesda, Maryland, US. The trial…
…President and General Manager of Aldevron’s Protein Business Unit. “By combining manufacturing strengths, from day one, IDT clients now can access Aldevron CRISPR proteins which are designed for clinical translation.”…
…and open the path to human trials of it’s potentially curative treatment for ADO2. There are currently no approved treatments for this disease and no other treatments currently in clinical…
…generation Covid-19 vaccines clinical trial ICON and the US Biomedical Advanced Research and Development Authority (BARDA) will execute a clinical trial to evaluate the effectiveness of next-generation Covid-19 vaccine candidates….
…a useful biomarker for disease progression. Potential drug targets to be investigated Robin Dart, former Wellcome trust funded PhD student at the Crick, postdoctoral clinical research fellow at King’s College…
The University of Oxford has revealed that researchers are currently in the advanced stages of preparing for a clinical trial of a Nipah vaccine using the ChAdOx1 vector. The scientists…
ICON, a healthcare intelligence and clinical research organisation, with the US Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response within the US…
IO Biotech, a clinical-stage biopharmaceutical company developing novel, immune-modulating cancer vaccines based on its T-win technology platform, has announced data from a pre-defined interim analysis related to the lung cohort…
…trials, most notably in oncology and autoimmune disease. “Rabies represents an ideal opportunity to provide rapid clinical validation of our novel vaccine technology given the large exposure-naïve population and established…
