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DDW Deputy Editor Reece Armstrong recently attended the Invest in Toulouse Virtual Round Table to [...]
AI in drug discovery eBook out now This 28-page DDW eBook, sponsored by Benchling, contains [...]
2 July 2020 From the race to the COVID-19 cure to the new manufacturing technologies that could be a game changer for stem cell therapies. The summer issue of DDW…
…thought that the immune system (especially B cells) has evolved to efficiently recognize such particulate antigens. Vaccines are now being developed to mimic natural viral structures, and such nanoparticle vaccines…
…gene replacement technology in human hematopoietic stem cells (HSCs) in Nature Biotechnology. The paper, entitled Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking, outlines technology…
…of respiratory airways, block binding, and entering the virus into the cells”, explains Prof Rimantas Kodzius from KTU Panevezys Faculty of Technology and Business. SARS-CoV-2 is a single- strand, positive-sense…
…was effective in killing neuroblastoma cells, leaving behind healthy cells. This is one of the first studies to show this in neuroblastoma cells and in tumour models. Dr Helen Bryant,…
…Another possibility would be to deliver the peptide on its own, allowing it to bind to the coronavirus spike protein outside of cells and be carried into cells with the…
…in T-ALL, compared to its greater-level of presence in B-ALL cells. Hence, SAMHD1 protects B-ALL cells, but not T-ALL cells, from the anti-cancer effects of nelarabine. The findings have crucial…
…the digital biology company Recursion has publicly released the world’s largest imaging dataset portraying therapeutic compound effects from over 1,600 approved and referenced molecules on SARS-CoV-2-infected human cells. The images…
…discovery, understanding the dynamic processes of cells provides an enhanced picture of drug pharmacology, enabling more reliable predictions of clinical responses earlier in the process. In this article, we highlight…
…COVID-19, uses the ACE2 receptor to enter cells, causing infection. Due to differences between the mouse and human ACE2 receptors, normal laboratory mice cannot be infected with SARS-CoV2. Transgenic mice…