Preclinical data has demonstrated that the oral small molecule OLX-07010 inhibits tau aggregation in a model for inherited tauopathies such as progressive supranuclear palsy (PSP) and frontotemporal dementia (FTD). Earlier…
…potential clinical benefit for people with RA and IBD. The paper was authored by Dr Asif Iqbal from the University of Birmingham and Professor Francesco Maione, Head of ImmunoPharma Lab…
…to predict who will benefit from carboplatin and docetaxel using a range of different biomarkers and suggest further investigation of these biomarkers in clinical trials is warranted. The presence of…
…your compound helps you avoid unnecessary clinical studies, costs, delays and more. This webinar will provide insights at a high-level related to regulatory drivers, investigatory objectives, and practical concerns for…
…likely to respond to a drug, before enrolling into clinical trials. The hope is that one day this could lead to fundamental changes in how we deliver personalised medicine.” Edited…
Research partners in the UK are progressing their orally available small molecule cancer immunotherapy drug into clinical development as a treatment for advanced solid tumours. Sosei Group and Cancer Research…
…engager approved for UK clinical trial The UK MHRA has granted Aleta Biotherapeutics a clinical trial authorisation to evaluate biologic ALETA-001 in a Phase I/II clinical trial in patients with…
In preclinical studies, a new pan-coronavirus papain-like protease (PLpro) inhibitor has shown a near complete reduction in SARS-CoV-2 viral load in the lungs. Infex Therapeutics has selected the clinical candidate…
…risks of your compound helps you avoid unnecessary clinical studies, costs, delays and more. This webinar will provide insights at a high-level related to regulatory drivers, investigatory objectives, and practical…
A new respiratory syncytial virus (RSV) vaccine candidate has achieved positive safety and immunogenicity results in a Phase I clinical study of RSV-naïve participants between the ages of six and…
…are always seeking new and innovative ways to optimise process efficiency while maintaining product integrity,” said Dr Michael Kress, Senior Vice President, Development Sciences and Clinical Supply, Merck Research Laboratories….
…technology capabilities with Icahn Mount Sinai’s deep understanding of gene delivery and expertise in cardiovascular research and clinical translation. “This project is a significant step for Evox as it expands…
…could be improved, such as avian influenza, mpox (monkeypox) or hantavirus. VDEC’s teams are already running Phase I clinical trials for a potential world-first vaccine against Crimean-Congo haemorrhagic fever, a…
…of the ongoing Phase II clinical trial of PT-112 in patients with late-stage metastatic castration-resistant prostate cancer (mCRPC). Scientists create compound that can block cancer metastasis Researchers from the University…
…able to accelerate the development of this promising antibiotic compound, by supporting clinical and pharmaceutical development activities, with the hope of getting it to patients where it is most needed.”…