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DDW Deputy Editor Reece Armstrong recently attended the Invest in Toulouse Virtual Round Table to [...]
AI in drug discovery eBook out now This 28-page DDW eBook, sponsored by Benchling, contains [...]
…therapeutic cancer vaccine is to instruct the patient’s immune system to recognise and eliminate cancer cells. The origins of using mRNA for delivery of cancer vaccines date back to the…
…immune system and more cytotoxic T cells which kill cancerous cells. Official comments “In recent years, there has been a lot of attention on whether combining immune checkpoint blockade, a…
…Institute of Cancer Research, London, said: “We wanted to understand why it seems more difficult for cells to copy repetitive DNA sequences than other parts of the genome. Our study…
…a combination of an Iduronate 2-Sulfatase (IDS) enzyme and antibody fragment to access the brain cells. The idea behind the treatment is that it breaks down the glycosaminoglycans (GAGs) that…
…a genetic blood disorder in which patient’s red blood cells change shape and become sticky, which can restrict blood flow through vessels distributing blood around the body. VOCs are a…
…double strand breaks (DSBs), an action which sensitises cancer cells to radiation treatment. The DNA Damage Response system (DDR) is activated by DNA damage, including DSBs in the genome, which…
…cause of autoimmune disease through its function to silence autoimmune memory T cells that accumulate at the disease site and which express LAG-3 as an “exhaustion marker. Immutep reported pre-clinical…
…prevent damage caused by heart attack, which is the leading cause of death worldwide. “The heart can’t regenerate muscle cells that die during a heart attack, which is why these…
…including an assessment of the next generation of stem cell derived products. You can also find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. Listen here…