…that its effects lasted over the 12 months of the trial means that we can proceed to the next stage of clinical trials.” The researchers injected between 5m and 24m…
…pivotal proof-of-concept testing clears the way to progress the Clamp2 technology in a range of research programmes. Project leader, Associate Professor Keith Chappell, said the preliminary clinical trial results were…
…Reece Armstrong comments on the post-Covid industry landscape. In the second article, Ben Folwell, Principal Consultant at Citeline, maps out how AI, swarm learning and open access to clinical data…
…of MPS across a series of applications in drug discovery and development. Context Around 90% of drug candidates reaching clinical trials fail, often due to poor clinical translatability between conventional…
…VP Clinical Development, Minoryx. “In patients with cALD, appearance of gadolinium-enhancing lesions typically precedes a phase with pronounced lesion growth and rapid clinical deterioration. Minoryx therefore wants to encourage adult…
…discipline across the continuum of biomedical research, including basic, translational, clinical, and epidemiological studies. Welm is the senior director of basic science at Huntsman Cancer Institute, a professor in the…
…the country has lower drug approval rates than other competitor countries, and that clinical trials are completed at a slower rate. It provides examples of companies such as AstraZeneca and…
…clinically focused on the US market. There will also be a focus on high quality non-US clinical stage biopharma assets seeking to access the US market. “Over the recent quarters…
…these areas, for example the Carbon Footprint for Decentralized Trials project. Accelerate the use of Real-World Data – The rise of wearables, internet of things (IOT) devices, social media and…
…risk clinical feature, defined as presence of EMD, BMPC >60% or B2M >5.5. All 38 patients had at least three prior lines of therapy. The interim CART-ddBCMA Phase I clinical…
…optimising preclinical and early clinical studies. Download this content-rich digital article to read about considerations for implementing and standardising high-dimensional immune profiling methods into drug development programmes. Learn about different…
…significantly extended lifespan in Caenorhabditis elegans, a simple model organism. KDM1A’s anti-cancer activities have already been established in both preclinical and clinical studies, including in colorectal and triple negative breast…
…a central role in pain signalling, in part through the release of neurotransmitters such as glutamate and GABA. The Cav2.2 (or N-type) calcium channel is the target for three clinically…
…showed that Verve-101 could meaningfully and durably lower LDL-C in these patients. We’re at an exciting moment for cardiovascular prevention where the management of ASCVD may fundamentally change.” heart-1 clinical…
…they sequenced the genomes of 85 S. Typhi samples obtained from people with confirmed typhoid fever from 2012 to 2019, plus an extra 10 from clinical infections in the UK…
