Upcoming Webinars

Where is the opportunity in the therapeutic antibody market?

In this free webinar, you will hear from Dr Jill O’Donnell-Tormey, CEO and Director of Scientific Affairs at Cancer Research Institute; Dr Roger Levy, Senior Global Medical Director, GSK Specialty Medicine; Dr Sheila Keating, VP of Immunology at Gigagen; as well as event sponsors Dr Milind Nigam, Leader – Scientific Solutions Consulting at Benchling, and […]

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Higher throughput bioanalytical methods accelerate the development and evaluation of advanced biotherapeutics

Successful development of advanced biotherapeutics relies on extensive characterisation and tight quality control. Characterising binding properties of complex biomolecules is a critical step. Biophysical data combined with functional assays are needed to predict efficacy and potency, optimise drug delivery, assess critical quality attributes, and improve biologics drug design. Traditional approaches have limited use in a complex […]

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Enhancing collaboration between sponsors and contract partners in drug discovery

Most contemporary drug discovery companies (sponsors) outsource some (or all) drug development to external contract partners, eg. Contract Research Organisations (CROs) and/or Contract Development and Manufacturing Organisations (CDMOs). Communication between sponsor and contract organisation is largely done via email and poorly structured Excel reports which is a highly manual, inefficient, and error-prone process. Additionally, sponsors […]

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CRISPR screening at scale: Achieving 1M cell data sets with an instrument-free, cost-effective approach

Pooled CRISPR screens offer the ability to knock out or perturb many genes in a single experiment from several hundred to tens of thousands of targets in parallel. Genome-wide screens are becoming the standard for drug discovery to power unbiased identification of drug targets across gene regulatory networks. Requiring single-cell genomics as the data output, […]

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Webinars on Demand

An introduction into fragment-based drug discovery: webinar

Fragment-based drug discovery (FBDD) is a method used for finding hit compounds as one strategy of hit identification (hit ID) in the drug discovery process.   Introduction into Fragment Based Drug Discovery, hosted by DDW and supported by WuXi AppTec, is now available to watch online.  Fragments are small molecules with a low molecular weight (less […]

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Tips and Tricks on Obtaining Quality Data from Biosensors for Cell Signalling Assays

Tips and tricks on how to obtain and analyse high quality data from live cell, high throughput assays of signaling dynamics. Genetically encoded fluorescent biosensors enable continuous recording of cellular signaling in live cells. This breakthrough technology provides unprecedented, real-time measurements of signaling dynamics, which is emerging as a critical determinant of physiological function and […]

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High throughput Octet BLI applications in early monoclonal antibody discovery

Charles River, Antibody Discovery group, has integrated computational immunology, antibody engineering and phage display technologies into its comprehensive antibody discovery platforms that rapidly deliver antibody hits or optimised variants with a range of affinities, cross-species coverage, and improved drug-like characteristics. Charles River uses label-free biosensors and other bioanalytical assays to support biochemical/biophysical characterisation of biotherapeutic […]

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Transforming lab automation for cellular applications

Automation has long been a buzzword associated with cutting-edge science, yet even in the most advanced labs it is usually only applied to specific assays and methods. However, by building automation across your full laboratory workflows and integrating it into existing protocols, Biotech R&D can be transformed. In this webinar, titled ‘Transforming lab automation for cellular […]

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Resolving complex biology with single cell and spatial multiomics

Single cell and spatial tools from 10 X Genomics are designed to deliver powerful, multiomic insights from complex disease samples that enable you to confidently fuel your target identification pipeline with the most promising candidates. Resolving complex biology with single cell and spatial multiomics was presented by Stephen Hague, Managing Lead Science & Technology Advisor […]

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AI in action: examples of AI across drug discovery

Drug discovery and development is a challenging multiparameter optimisation problem. Harnessing the power of artificial intelligence (AI) can help accurately predict the behaviour and properties of small molecules. In this on-demand webinar from X-Chem you will see: How AI and DNA-encoded library (DEL) screening are transforming early phase drug discovery How this can impact all stages […]

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Generating and validating critical antibody reagents

Antibodies are critical reagents applied in multiple biological areas, such as scientific research, therapeutics, and diagnosis. High-quality and reliable antibody reagents are the foundation of good assay performance. To learn more generating and validating critical antibody reagents view this free event hosted by DDW and supported by Sino Biological. The webinar took place on 16 June […]

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CRISPR-Cas9 screening: a powerful approach to drug discovery

View this webinar by DDW and supported by Horizon Discovery which examines CRISPR-Cas9 screening and how it offers a powerful approach to advancing drug discovery and the understanding of genetic disease. The event took  place on 9 June 2022. View the webinar here. Joanna Gawden-Bone, Manager, Cell Based Screening, Horizon Discovery will explain how leveraging CRISPR-Cas9 […]

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Accelerating cellular therapy discovery with the next generation BioELN

Cellular therapeutics like CAR-T have revolutionised cancer treatment and hold immense promise in other areas of unmet medical need. Developing a new therapeutic cell line is no small task and requires the design and tracking of molecular tools, viral vectors, pluripotent stem cells and more. With projects spanning weeks and potentially multiple scientists, how can […]

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A breath of fresh air: novel approaches to human lung disease modelling for accelerated drug discovery

DDW was delighted to work with CN Bio on an exclusive event which focussed on novel approaches to human lung disease modelling.  The free event took place on 29 March at 3pm.  It covered:  Accelerating the discovery of new therapeutics for treatment of lung injuries using patho/physiology mimicking models. (Speaker Professor Wojciech Chrzanowski, Faculty of […]

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Kill the tumour, spare the healthy tissue. Ultra high-content imaging enables target discovery for CAR T cell therapy

In this free webinar, Dr. Christoph Herbel presents a newly developed workflow which combines flow cytometry–based screenings with high-parameter imaging to identify and validate new tumour markers in an unbiased approach.   The event, Kill the tumour, spare the healthy tissue. Ultra high-content imaging enables target discovery for CAR T cell therapy, was hosted by DDW and supported by Miltenyi Biotec.  It took place on 14 Dec, 4PM GMT, 5PM CET.  Watch on Demand […]

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Sensitive signature peptide quantification using accurate mass spectrometry

Emerging advancements in protein biotherapeutics are driving the need for more sensitive and accurate bioanalytical methods for their quantification. Serving as an orthogonal technology to the traditional ligand binding assays (LBAs), LC-MS has been routinely adopted for quantitative measurement of protein levels in bioanalytical laboratories. While various MS approaches have been investigated by researchers, bottom-up […]

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Deriving context from immunological data with advanced flow cytometry

Advances in treatments for human diseases, including cancer, rely on the ability to gain detailed information into the function, modulation, and variation of the immune system in response to stimuli or immunological challenge. Insights derived from these data have, for example, revolutionized cancer treatment by enabling the development of adoptive cell transfer therapies, such as […]

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Challenges and opportunities in protein degradation

Many small molecule inhibitors have been approved as cancer therapeutics, but they can confer mutation-based drug resistance and many potential cancer targets remain “undruggable”. One emerging cancer therapeutic strategy that shows promise for drug development is the use of targeted protein degradation (TPD). This approach has many advantages, including the ability to aim at previously […]

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Using an automated CE-SDS platform in efficient biosimilar comparability studies

This event provided expert insight from Dr. Richard L. Easton, Technical Director of Structural Analysis at BioPharmaSpec. He provides data from studies with monoclonal antibodies, heavily glycosylated species and PEGylated species showing how the Maurice platform can be used to provide reliable insights into the structure of different types of biopharmaceuticals, including assessments of size […]

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A new path to the clinic using CRISPR-Cas screens and cell panel drug screens

Navigating from target identification to validation can be a complex process, so it makes sense to find the right assays and models to validate or refute a hypothesis ahead of spending vast amounts of money on clinical trials. CRISPR-Cas gene editing has made an impact in this space with forward genetic screens being seen as […]

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