Worldwide News

News round-up by DDW’s Megan Thomas for 10-14 January, 2022  Studies, approvals and research are at the heart of drug discovery, which has been exemplified in this week’s drug discovery news. Megan Thomas has rounded up her top five stories of the week.   Vaccine-like mRNA injection can be used to make CAR-T cells  A study from […]

Collaboration within the drug discovery sector is well documented, says Lu Rahman. During the Covid-19 pandemic we have seen great examples. Take Pfizer and BioNTech or the work between Carterra and Eli Lilly Company to create bamlanivimab, a Covid-19 therapeutic. Collaborative work has created vaccines and therapeutics which are helping us combat this coronavirus.   […]

With SLAS2022 confirmed to go ahead as both an in-person and hybrid event, the Innovation Award finalist presentations will take place on February 8, from 10AM- 5PM, and will be live-streamed to the online audience.   What is the SLAS Innovation Award? The SLAS Innovation Award consists of a $10,000 check presented to a winning presenting […]

Brad Loren, Matthew Marrone, and Christopher Singer, of intellectual property and technology law firm McAndrews, Held & Malloy, on quantum computing and its benefits to drug discovery.  Explaining quantum computing and its promise  Before we explore how QC can benefit drug discovery and drug development, let us first take a step back and explore what QC actually […]

Otsuka Pharmaceutical and Astex Pharmaceuticals’ oral fixed dose combination of decitabine and cedazuridine (ASTX727) for the treatment of Acute Myeloid Leukaemia (AML)1 has been granted orphan-drug designation (ODD) by the European Commission (EC).  What is ALM?  AML is the most common form of acute leukaemia in adults2. Within Europe, there is an increase in the incidence […]

Sanj Kumar outlines the positive role that digital technology has played in ELRIG events and how the organisation has harnessed the use of technology even when events have gone back to face-to-face.  Scientific conferencing plays a key role in bringing together researchers and suppliers to share data, ideas and spark new innovations. Organisers of face-to-face events with large numbers of […]

With the recent clinical approval of sotorasib, the first drug targeting KRASG12C, a milestone was reached in the treatment of lung cancer.  While initial drug response is remarkable, resistance occurs rapidly and most patients relapse. A better understanding of the mechanisms of action involved in the response and the development of resistance to these drugs is required. Interestingly, KRASG12C inhibitors induce profound changes in the expression of genes involved […]

The Winter issue of the Drug Discovery World Magazine is out now.   Featuring Specialty Spotlight on Ophthalmology, the magazine is available to download and read for free on the DDW App.   Key features of the Winter Issue include: How Quantum Computing Can Benefit Drug Discovery, Why The Emergence of Targeted Protein Degradation is So Exciting, plus exclusive interviews and articles on cancer research, synthetic biology and rare variant contribution to human disease.   Exclusive  DDW &  SLAS2022 supplement   This issue is also accompanied by an exclusive DDW & SLAS2022 supplement ahead of SLAS2022 in Boston, […]

China-based Sinocompound Catalysts has partnered with InCatT to launch a specialist Catalyst Screening Service for pharmaceutical and fine chemical companies looking to optimise their reactions.   The service  The new service draws on InCatT’s experience in screening homogeneous catalysts combined with Sinocompound’s expertise in custom synthesis, scale-up and manufacturing of advanced catalysts and ligands. By combining these capabilities under a single offering, it is said that […]

Discover how process optimisation utilising automated synthetic biology solutions can remove the antibody sequence cloning bottleneck that divides high-content lead identification and downstream high throughput characterisation. If your work involves antibody discovery or process improvement in recombinant cloning don’t miss this whitepaper illustrating how Codex DNA’s synthetic biology solutions can accelerate antibody discovery workflows. In […]