Leaving the Wild West Era of Lipidomics

Leading research from European Journal of Lipid Science and Technology How many different types of diseases are there in the world? How will we ever be able to find cures for them? We might not be able to do so for all of them, but we may be able to develop better treatments. Scientific and […]

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Disrupting Drug Discovery From Assay Development to Lead Compound

High-throughput screening remains one of the most powerful, unbiased approaches for small molecule drug discovery. In this white paper, SAMDI Tech CSO, Zack Gurard-Levin, discusses the important aspects to consider when choosing the right methodology for drug discovery. Learn: Traditional label-dependent approaches vs. novel label-free technologies How researchers determine which methodology offers the most promising […]

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Do you need a custom monoclonal antibody for your next project?

Selecting the right custom antibody provider is an important decision. It can mean the difference between a breakthrough or failure. That’s why it matters in how and where your antibodies are made. Learn what sets Bethyl custom monoclonal antibodies quality and service apart. Discover the top reasons why you should choose Fortis Life Science for […]

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Advancing quantitative analysis of targeted protein degrader compounds

Small molecule drug discovery is expanding beyond traditional strategies focused on identifying compounds that inhibit or block the activity of proteins that cause disease. A newer approach is to selectively target proteins for removal from the cell using degrader compounds. Proteolysis Targeting Chimeras (PROTACs) and immunomodulatory (IMiD) molecular glues are examples of small molecule degraders […]

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Finding a needle in the haystack: identifying actionable biomarkers from the plasma proteome

In a study published in Neurology, a group from Alnylam Pharmaceuticals used large-scale protein screening assays to simultaneously analyse many proteins in vast numbers of patient serum samples. This cutting-edge approach allowed them to discover a novel biomarker of hereditary transthyretin-mediated (ATTRv) amyloidosis disease onset and progression. ATTRv amyloidosis, caused by mutation of the transthyretin […]

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Whitepaper: FDA guidelines for GMP of API

One of the key elements of quality control in pharmaceutical manufacturing is cGMP compliance. As your product moves closer to market, cGMP requirements change and become more stringent. Dalton Pharma Services has created a whitepaper to download, FDA Guidelines for GMP of API. Featured in this whitepaper: API and GMP overview FDA API regulations including: […]

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Take your drug to market faster

The pressure to take your drug to market faster is increasing. To achieve a successful journey to the first clinical trial phase in the fastest time possible, we have identified three key elements we are addressing in this eBook. Comply with audit requirements and relevant certifications Drive process efficiencies with increased speed whilst not sacrificing […]

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App note

Cell culture just got smarter

The OLYMPUS Provi CM20 incubation monitoring system can be used to develop methods for efficient quality control and data management within your cell culture workflow. In this application note, discover how the quantitative data collected from the CM20 enabled users to compare and detect variable efficiency of differentiation of Human iPS cell lines for generation […]

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Systems-level analyses reveal that children with the COVID-associated inflammatory syndrome, MIS-C, display a unique immunological profile

Olink has created a summary article of a study recently published by Consiglio et al. in Cell. This study focuses on the rare cases when children develop Multisystem Inflammatory Syndrome in Children (MIS-C) in response to infection by the SARS-CoV-2 virus. Typically in these cases the syndrome manifests four to six weeks after infection, producing […]

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White paper: Improve the drug discovery tool box

Making good decisions in the drug discovery process requires software to effectively manage the size and complexity of multiparametric datasets. Companies that most quickly and accurately identify key drug discovery parameters will win the race to identify the most appropriate targets and develop medicines to affect them.

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