Author Archives: Diana Turner

A laboratory mouse
#Animal models #Animal testing #Genetic editing #Genetics #Phenotyping

NIH renews knockout mouse project for 3rd time

The University of California, Davis, has received over $12 million from the National Institutes of Health for the third and final five-year phase of the Knockout Mouse Phenotyping Project (KOMP2). ‘Knockout’ mice are bred in a laboratory with specific genes silenced or ‘knocked out’. They have been valuable tools for… Read More

#News

Small cell lung cancer
#Cancer research #Cancer treatment #Lung cancer

Combination therapy halts lung cancer tumour growth in mice

An experimental combination of two drugs halts the progression of small cell lung cancer, the deadliest form of lung cancer, according to a recent study. The discovery was made by researchers at Washington University School of Medicine in St Louis, Grenoble Alpes University in Grenoble in France, and The University… Read More

#Cancer Research #News

Natural killer cells
#allogeneic cell therapies #Cancer immunotherapy #Cancer research #Cancer treatment

Zelluna Immunotherapy secures funding for cancer treatments

Investment from Takeda ventures will fund the development of Zelluna Immunotherapy’s allogeneic T Cell Receptor Natural Killer (TCR-NK) cells for the treatment of cancer. The funds will enable the advancement of a lead TCR-NK product through manufacturing to Clinical Trial Application (CTA) / Investigational New Drug Application (IND) readiness and,… Read More

#Business & Investment #Cancer Research #News

Patient on ventilator
#Covid-19 #Diabetes #Long Covid

Diabetes drug could prevent severe Covid

A recent study by the University of Colorado School of Medicine shows that diabetes drug metformin is effective for preventing severe illness from Covid-19. The CU School of Medicine was part of a multi-site clinical trial into the effectiveness of metformin, ivermectin and fluvoxamine in non-hospitalised adults with Covid-19. … Read More

#Covid-19 #Editor's Choice #News #Trending News

Mechanisms of endocytosis
#Endocytosis #Protein chemistry / Proteomics #Tokyo University of Science

Austrian-Japanese study reveals protein’s role in endocytosis

Scientists from Tokyo University of Science have shed light on how various molecules are recruited in endocytosis, a cellular process of bringing in different types of materials from the outside. The results suggest key regulatory functions of the yeast Eps15-like protein Pan1p. The findings provide important insights into the process,… Read More

#News

San Diego skyline
#BioLabs #Charles River #Drug development #Drug discovery

Charles River expands contract vivarium space on West Coast

Charles River Laboratories has added five new Charles River Accelerator and Development Lab (CRADL) locations in California and Washington.  CRADL provides flexible, turnkey vivarium rental space supported by Charles River’s technical and veterinary support expertise in key biohubs. This allows clients to start new projects, accelerating the early stage… Read More

#Business & Investment #News

Kanekwa Zyambo and Dr Morrison
#Biomedical research #Gut microbiome #Sub-Saharan Africa #University of Glasgow #University of Zambia

Scottish and Zambian researchers tackle environmental enteropathy

Scottish scientists are teaming up with researchers from Zambia to find new ways to diagnose and treat a condition which affects millions in Sub-Saharan Africa.   Ms Kanekwa Zyambo, from the University of Zambia, is spending two weeks at the Scottish Universities Environmental Research Centre in East Kilbride to… Read More

#News

Vials for medical research
#Antibodies #Biomedical research #Drug development #Drug discovery #In vitro

New anti-evolocumab antibodies could aid drug development

Bio-Rad Laboratories has introduced a range of type 1 antibodies that inhibit the binding of evolocumab (Repatha) to its target, human proprotein convertase subtilisin/kexin type 9 (PCSK9), a protein that has been shown to play a key role in the regulation of cholesterol levels.  These sequence-defined, recombinant antibodies are… Read More

#News

Diabetes patient injecting insulin
#Autoimmune disease #Biomedical research #Cardiovascular disease #Diabetes #Statins #Type 2 diabetes

Study: autoimmune disorders increase cardiovascular risk

Individuals with an autoimmune disorder have a substantially higher risk of developing cardiovascular disease, a large epidemiological study has revealed.  The research – led by KU Leuven in collaboration with colleagues in the UK, including the University of Glasgow, and published in The Lancet – shows for the first… Read More

#News

Chronic myeloid leukaemia
#Cancer research #European Commission #Leukaemia #Novartis #Orphan drugs #Scemblix #STAMP inhibitor

European Commission approval for chronic myeloid leukaemia drug

The European Commission (EC) has approved orphan drug Scemblix (asciminib), providing a new treatment option for patients who are intolerant or resistant to tyrosine kinase inhibitors (TKIs). It is approved to treat adult patients with Philadelphia chromosome-positive chronic myeloid leukaemia in chronic phase who have been previously treated with two or more… Read More

#Cancer Research #News

SARS-CoV-2 virus particles
#Antibodies #Biomarkers #Clinical trials #Coronavirus #Covid-19 #Drug development #SARS-CoV-2

SARS-CoV-2 antigen levels could predict patient outcomes

The amount of SARS-CoV-2 antibodies in the blood of patients hospitalised with Covid-19 could be used to predict illness severity and other clinical outcomes.  A new study, published in the Annals of Internal Medicine, shows that higher levels of viral antigen in the blood, which… Read More

#Covid-19 #News

#AI / data analytics / healthtech / informatics #Cancer research #Imaging #Lung cancer #Oncology

CIAN Lung: Exploring the potential of real-world data in lung cancer research

This article is sponsored by BC Platforms. Lung cancer ranks among the most prevalent and fatal cancers worldwide, prompting the need for improved treatment outcomes. Effective management relies on understanding tumour characteristics, including histology, clinical staging, and biomarkers. Despite progress in targeted therapies, ongoing research is… Read More

#News