Winter 2017/18 Teasers
Drug Discovery World
New tools to enhance the antibody drug pipeline
By Dr Robert Ford & Dr Toni Hoffmann

Therapeutic antibodies are the fastest growing class of drugs, with continuous increases in the number of innovator and biosimilar drugs in development.

Drug development and clinical trials necessitate the ability to specifically, sensitively and reproducibly measure the concentration and bioavailability of these drugs in pharmacokinetic assays. We discuss the rise of therapeutic antibodies in drug discovery in favour of traditional small molecules and issues around the development of these biologics, including their tracking with antiidiotypic antibodies. We will examine new tools that are entering the market to offer solutions that can speed development timelines and address problems of reagent reproducibility...

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