Spring 2018 Teasers
Drug Discovery World
The Cancer Conundrum increasing clinical success
By Lubna Hussain

Increasing clinical success by implementing improved methodologies in early phase drug discovery. Using primary cells and 3D culture models to enhance cancer drug discovery.

The high stakes of drug discovery and development lead pharmaceutical companies to be meticulous in ensuring a target is validated and that compounds are effective against this target in order to have the best chance of developing a successful drug. Taking into account the long-term investment of both time and money to find, test and develop a therapy for a disease like cancer, pharmaceutical companies need to better recognise the importance of using more robust methods, such as primary cells and 3D culture models, in early phase drug discovery to decrease the risk of late-stage failures...

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