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Translational Chemical Biology: Gap assessment for advancing drug discovery, development and precision medicine. Winter 16

As yesterday’s lead molecule enters today’s clinical trial, the standard operating script seems to call for product developers and clinicians to push away the originating basic scientists, lest their lofty impractical ideals disrupt a delicate balance of strategic compromise. Indeed many scientists may not understand the competing push and pull of efficacy versus toxicity and quality versus production costs.

Individualised Systems Medicine next-generation precision cancer medicine and drug positioning.

A growing number of oncology drugs are currently clinically available and more than a thousand compounds are being developed for oncology indications.