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The increasing impact of precision research models on drug discovery and development.

Animal models are the standard by which we gain insight into the complex biological processes that underlie normal human physiology and disease states. Rodent models such as rats and mice have been used to understand various aspects of human physiology, disease and treatment outcomes.

A novel approach by AstraZeneca to monitor primary DMPK assay performance & understand the inter and intra site assay variability.

An integral part of early drug discovery at AstraZeneca is the process known as the Design Make Test Analyse (DMTA) Cycle. DMTA relies heavily on chemical synthesis and primary screening being delivered within a quick turnaround time.