Therapeutics
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Enabling the promise of Stem Cells. Spring 11

By Robert Shaw and Dr Jeff Till
The remarkable potential of stem cells to generate several hundred differentiated cell types is driving their use for regenerative medicine and for supporting the traditional drug discove...
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Making Early Access Real: getting treatments to patients with no other option. Winter 10

By Dr Rav Seeruthun
For patients who have no other option to treat their condition, early access to drugs in clinical development can be critical. As a trained physician, there is an intrinsic understanding ...
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New ways to optimise therapeutic and diagnostic antibodies. Winter 10

By Dr Markus Enzelberger
Monoclonal antibodies are the fastest-growing category of research within the biotech and pharmaceutical industries. Several monoclonal antibodies are listed in the top 10 selling blockbu...
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New mechanisms and expanded indications for biologic therapies: a perspective on immunology research and development. Fall 10

By Dr Susan B. Dillon
Over the past decade, the introduction of biologic therapies has had a profound impact for millions of patients with immune-mediated arthritides, inflammatory bowel diseases and plaque ps...
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New trends and therapeutic approaches for the management of diabetic retinopathy. Summer 10

By Dr Didier Pruneau
Diabetes mellitus is a growing epidemic that has become a global public health problem. The long-term complications of diabetes include retinopathy, the leading cause of blindness and vis...
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Stem Cells for cellular therapy space. Spring 10

By Dr Enal S. Razvi and Dr Gary M. Oosta
This article explores the emerging market landscape vis-à-vis the use of stem cells as cellular therapeutics. For more than 40 years, hematopoietic stem cells have been utilised as cellu...
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Stem Cell Therapies: assessing the commercial opportunity. Summer 09

By Su Webber, Andrew Millest and Mark Williams Restructuring and reorganisation is routine and relentless in the pharmaceutical industry, with a future focus essential for effective strategic decision making. In recent years, small mo... Read more...

Stem Cell Applications and Opportunities in Drug Discovery. Spring 09

By Dr Mark A. Thiede The high attrition rate of late stage drug candidates has led the pharmaceutical and biotech industries to a reassess the in vitro models used to select and validate drug targets and subs... Read more...

Building a robust portfolio of new medicines. Winter 08

By Dr Timothy N.C. Wells Malaria is one of the biggest killers of our time. Current estimates from the World Health Organisation (WHO) suggest that more than 250 million people are at risk worldwide1. More signif... Read more...

Treating rheumatoid arthritis with DMARDs and biologics. Fall 08

By Dr William E. Fogler Continuing research efforts that further refine our understanding of the pathobiological mechanisms in RA has, in turn, led to the development of novel DMARDs acting on these mechanisms. Read more...

Targeted remodelling of the diseased lung with biopharmaceutical agents. Fall 08

By Dr Edward E. Berger Emphysema is a progressive, debilitating disease that affects approximately 4.1 million people in the United States1 or roughly 1% of the US population2. The disease is characterised by d... Read more...

HIV Therapy past, present and future. Summer 08

By Dr Laura Waters Since the identification of HIV in 1983 and licensing of AZT in 1986 we now have more than 20 agents available for HIV treatment from five drug classes. This article will review recent ad... Read more...