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Enterprise ELNs as a foundation for preclinical drug development. Summer 10

By Simon Beaulah, Dr Paul Denny- Gouldson and Dr Scott Weiss
To have real business impact within preclinical drug development, Enterprise ELNs (Electronic Laboratory Notebooks) must provide a secure, scalable and searchable data management backbone...
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Leveraging research informatics to accelerate drug discovery. Winter 09

By Dr Anirban Ghosh and Siddharth Sawhney
Research informatics has a vital array of tools which can advance the speed and success rate of drug discovery. This article discusses that if pharma companies want to benefit from these ...
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Integrating computational methods and drug discovery – avoiding pitfalls in chemical space. Winter 09

By Alexandre Ismail and Professor Philippe Manivet
The immensity of the task in discovering suitable molecules for development among the vast number which are theoretically available is well stated. With 90% of potentially efficacious com...
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Role of image informatics in accelerating drug discovery and development. Winter 2003

By Robert Dunkle
There is a new category of informatics that is proving itself essential to the acceleration of drug discovery and development. Image informatics is the systematic use of image data as a m...
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LIMS vs ELNs arch enemies or best of friends? Summer 09

By David Morris
Since the first appearance of laboratory information management systems (LIMS) in the late 1960s, this technology has become commonplace in many, if not most, research and commercial labo...
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Biologists Flirt with Models. Spring 09

By Gordon Webster
The enormous challenge posed by the complexity of biological systems represents a potential intellectual impasse to researchers and threatens to stall future progress in basic biology and...
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in silico structure-based drug design – SHIFTING THE BOTTLENECK? Spring 2003

By Dr Jonathan Heal Drug Discovery
The use of in silico methods in drug design has grown significantly in popularity over the past couple of years. Indeed many pharma companies have already adopted some type of virtual scr...
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High content screening – the next challenge: effective data mining and exploration. Winter 2008

By Dr Kurt Zingler and Dr Stephan Heyse
The use of high content screening within HTS is growing and with many past hurdles now overcome, the need for effective tools for data analysis is becoming paramount.
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Data Overflow Progress in Automating and Streamlining Data. Summer 2008

Summer 2008 The genomic world moves faster and faster. The pool of data has exploded exponentially in the past few years due to the growing knowledge about the relevance of genomic findings for medic... Read more...

Seeing is Believing. Summer 2006

By Dr Christopher Ahlberg There is a growing pressure in today’s climate for pharmaceutical companies to find tomorrow’s wonder drugs and dominate the major market segments. Recently, they have also been under... Read more...

Finding the critical path: applying the semantic web to drug discovery and development. Fall 05

By Dr Eric Neumann There is much happening in drug development these days: new target classes, increasing costs, new forms of high throughput screening, and the promise of personalised medicine. But of all ... Read more...

Computer-aided design: progress towards more rational drug discovery. Summer 05

By Dr Wolfgang H.B. Sauer Drug discovery is a science, a craft and an art, and often it requires a fair amount of serendipity or plain luck to succeed. Success is rare and costly, as evidenced by numerous reports ... Read more...

ONTOLOGIES semantic networks of pharmaceutical knowledge. Summer 05

By Dr Stephen P. Gardner In the current climate making information more transparent to internal R&D staff and to external audiences such as regulators and consumers is crucial to business effectiveness. A new gen... Read more...

Redefining drug discovery informatics. Summer 05

By Bryan S. Koontz As the pharmaceutical industry changes in response to unprecedented challenges, information technology supporting the drug discovery process must evolve and be redefined in order to impro... Read more...