3D Cell Culture developments to improve in vitro analyses. Spring 11By Prof Stefan Przyborski Improved in vitro models are required to aid the identification and assessment of candidate molecules for pharmaceutical development. Conventional cell culture models involve the growth o...
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Bulk Reagent Dispensers: ubiquitous liquid handling tool for microplate filling! Fall 10By Dr John Comley The initial success of the bulk reagent dispenser (BRD) as an automated liquidhandling product can be attributed to its simplicity and low cost. Its current role as an essential dispensin...
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Mass Spectrometry in Drug Discovery and Development. Fall 10By Dr Stephen Naylor and Paul T. Babcock Mass Spectrometry is a mature technology predicated on a premise demonstrated almost a century ago. It is widely used in most scientific disciplines involving basic research or industrial...
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High throughput flow cytometry for discovery at UNMCMD and the NIH Molecular Libraries Initiative. Fall 10By Dr Larry A. Sklar and Dr Bruce S. Edwards Commercial flow cytometers became widely established in research and clinical laboratories in the 1980s. Once the domain of immunologists and hematologists for cell sorting and analysis, ...
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REAL-TIME PCR - where we are and where are we heading. Spring 10By Dr Mikael Kubista Quantitative real-time PCR is becoming mature technology for the quantification of nucleic acids. It is spreading wide outside its original use in the research laboratories, becoming pref...
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Compound Profiling: size impact on primary screening libraries. Spring 10By William Downey, Cindy Liu and Dr Jennifer Hartigan A recent report examines the trends in utilisation of compound libraries, as well as the impact of profiling on the size of screening decks. The drivers for choosing between large or focu...
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Automation Of Solid/Powder Dispensing: much needed, but cautiously used! Summer 09By Dr John Comley This article investigates solid/powder dispensing in pharma and biotech, examines where it is most used, whether there exists a need to apply automation and what is motivating its wider u...
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Restructuring proteomics to enable personalised cancer care. Summer 09By Dr Henry Rodriguez The genomics community has made great strides in our understanding of the molecular basis of cancer and these advances are slowly beginning to change the way we diagnose and treat patient...
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