Custom Carbon-14 Radiolabelling: investing to meet new challenges. Winter 09By Dave Roberts One consequence of an increasing demand from regulators for robust quantitative data on the behaviour of new drugs in man and for information on the fate of pharmaceuticals in the environ...
|
Overcoming the limitations of chemical structure. Summer 09By Dr Andy Vinter, Dr Steve Gardner and Dr Sally Rose The pharmaceutical business has been profoundly hampered by a ubiquitous and unexpected obstacle – the way it draws its chemical compounds. Scientists, patent agents and business decisi...
|
Microwave-Assisted Orgainc Synthesis - an Enabling Technology with Disruptive Potential.. Fall 08By Dr Anil Vasudevan Since the original publications on the benefits of conducting organic reactions in a microwave by Gedye1 and Majetich2 in the mid-80s, the uptake of this technique was sluggish at best fo...
|
Zebrafish: a versatile in vivo model for drug safety assessment. Fall 06Dr Wendy Alderton and Dr Stéphane Berghmans Safety pharmacology has become an integral part of non-clinical safety assessment for new chemical entities in the past two decades1.The relative novelty of this discipline has granted it...
|
Medicinal Chemistry: progress through innovation. Summer 06By Dr Terry Hart Medicinal chemistry is a specialised science that has evolved to encompass a broad range of disciplines concerned with the identification, synthesis and development of drug-like compounds...
|
Microwave-assisted synthesis in the pharmaceutical industry a current perspective and future prospects. Summer 06By Dr Richard Wagner In the past five years there has been a dramatic upsurge in the use of microwave heating within the pharmaceutical industry to facilitate the chemical synthesis of new chemical entities.T...
|
The Role of the Medicinal Chemist in the Drug Discovery Process: current status and future prospects. Winter 05By Dr Stevan W Djuric The need for the pharmaceutical industry to produce a constant stream of new NCEs has never been more paramount but with constantly changing R&D paradigms what is the role of the modern m...
|
|
|
