Spedia-NMR' Gains Momentum
Unique to Spinnovation Biologics - the new division of Spinnovation Analytical BV (Nijmegen, The Netherlands) - Spedia-NMR™ has shown itself to be faster and more reproducible than liquid chromatography (LC)-based methods for cell culture media analysis. Spinnovation Biologics now provides NMR services to 20 major biotech companies, one of which is in the world top 10 Biopharma. The number of companies realising the benefits of Spedia-NMR™ is increasing every month, with 25 more biotechs currently evaluating the benefits of the service.
Spedia-NMR™ provides rapid, quantitative multiplex analysis of spent cell culture media, quickly identifying which feed components are most influenced by process change. Results include information on the production and accumulation of metabolites and toxic components.
Spedia-NMR™ is able to evaluate over 50 analytes at a time providing robust and cost efficient results with ideal linearity (R >= 0.99) over a large dynamic range (from 10 µM to 0.5 M) and limit of detection at approximately 1 µM. The service provides a detailed analysis including volatile metabolites and can even identify unanticipated unknowns, saving the time and cost of multiple analyses.
“The increasing uptake of Spedia-NMR™ services by Biopharma and biotech clients reflects a high demand for high throughput, detailed analysis of bioprocesses”, commented Dr. Frederic Girard, CEO of Spinnovation Analytical. “Our clients are using the Spedia-NMR™ data to optimize and standardize conditions in preparation for large-scale manufacturing of biologics, which they can do within a far shorter timeframe using our technology.”
Spinnovation Biologics offers Spedia-NMR™ alongside a wide range of complementary analysis methods including LC-MS, LC-NMR, LC-SPE-NMR, LC-SPE-NMR-MS, for troubleshooting in bioprocess and performing simple to complex profiling and characterization of biologics and biosimilars (including peptides, proteins, oligo/polysaccharides). All services are available on a contract or pay-per-sample basis to suit individual client requirements.
Further information including case studies demonstrating the new Spedia-NMR™ technology, can be found at: www.spinnovation-biologics.com