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Integrated Informatics Workflows to Automate Antibody Drug Conjugate (ADC) Characterization

Weibin Chen of Waters describes a characterization approach for antibody drug conjugates (ADCs) that uses both LC/UV and LC/UV/MS along with informatics to automate comparability assessments.

In this poster an integrated informatics workflow with UNIFI was developed to streamline data acquisition, processing and reporting for ADC analysis by LC/UV and LC/MS so that information from multiple analytical techniques can be effectively synergized for rapid and quantitative assessment of comparability of ADCs.