DDW ARTICLE DATABASE

THIS MONTH'S LIFE SCIENCE MOVIES
Superheroes
SpectraMax i3 Multi-Mode Detection System
See how you can do more with your microplate reader than you ever imagined.
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Waters
Bioanalysis of Oxytocin
Ultrasensitive Quantification Assay for Oxytocin in Human Plasma Using an LC/MS Microfluidics Platform
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I, robot. I, the future

Richard Holland
The Pistoia Alliance, whose membership includes most of the world's major pharmaceutical companies, technology vendors and publishers is keenly interested in discovering ways in which innovation through pre-competitive collaboration can be used to explore & exploit the stream of new technologies that become available.
 

Fusion Therapy - a new approach to combining treatments

Fall 2016 By Dr Thomas Mehrling
Increasingly, oncology agents are being used in combination. However, with complications such as drug resistance and unfavourable side-effect profiles, researchers have been looking for new ways to enhance treatment effect and tolerability.
 

3D cellular imaging - advances and considerations for high-content screening

By O. Joseph Trask, Dr D V. LaBarbera and Dr K Quick
Commercially available high-content imaging (HCI) systems, introduced in the 1990s, have provided the scientific community with a platform that offers a unique set of tools ideal for advancing high-throughput biological discoveries and therapeutic development.
 

Cell and gene therapies - the emerging fourth pillar of healthcare systems

Fall 2016 By Keith Thompson
As the CEO of an organisation that deals exclusively in cell and gene therapies, it is no surprise that I would champion the emergence of these products as the fourth pillar of medicine alongside small molecules, biologics and devices.
 

Breath based biomarker detection - informing drug development & future treatment regimes

By Billy Boyle and Dr Mike Murphy
The approval of liquid biopsy test for the diagnosis of non-small cell lung cancer (NSCLC) demonstrates how biomarker-based detection tools are becoming important components of precision medicine-based drug treatment regimes.
 

CRISPR/Cas9 – transforming gene editing in drug discovery labs

Fall 2016 By Dr John Comley
It is evident from a recent market survey on gene editing in drug discovery that CRISPR/Cas9 is now recognised as the superlative method when attempting a gene knockout or when introducing defined mutations, insertions or modifications to the genome.
 

An Update on Hepatitis B Therapies

Fall 2016 By Dr John Sullivan-Bolyai
The hepatitis B crisis is a worldwide unmet medical need. Hepatitis B (HBV) is the cause of a silent epidemic that has resulted in a worldwide healthcare crisis. Despite the significant burden it places on communities across the globe, hepatitis had been mainly ignored as a health and clinical development priority until recently (1)
 

Full length isoform sequencing yields a more comprehensive view of gene activity

Fall 2016 By Luke Hickey
RNA-seq has revolutionised how scientists can interrogate gene expression. But after years of performing RNA-seq studies with short-read sequencers, many have realised that there is more to be discovered.
 

Enzo Launches New Nanopolymer Immunohistochemistry Detection Reagents

Enzo have introduced a new line of several in situ hybridization (ISH) and immunohistochemistry (IHC) reagents and their complementary blocker/diluents. These products are offered as higher sensitivity and lower background improvements upon their existing product lines
 

Gilson Launches EXTRACTMAN Magnetic Bead Extraction Platform

Gilson EXTRACTMAN, based on Exclusion-based Sample Preparation technology from Salus Technologies, offers a fast and reliable option to isolate proteins with affinity methods using paramagnetic beads, especially in cases of weak protein interactions or protein interactions with short half lives.
 

Bio-Rad Announces CE IVD Marking of Its QX200 Droplet Digital PCR System

Bio-Rad Laboratories today announced CE IVD marking for its QX200 Droplet Digital PCR System, the first digital PCR system with the CE IVD mark for use as an in vitro diagnostic (IVD) in the European Union.
 

Bio-Rad Launches ddPCR CHO and E. coli Kits for Direct Quantification of Residual Host Cell DNA

The new ddPCR CHO Residual DNA Quantification Kit and Residual DNA Quantification Kit allow for direct quantification of host-cell DNA impurities in biopharmaceuticals purified from bacteria (E. coli) or mammalian cells without the need for upfront nucleic acid purification steps. The kits are designed for use with Bio-Rad’s Droplet Digital™ PCR Systems.
 

Enzo launches an ultra-sensitive and highly specific Total PSA (human) ELISA Kit

Enzo Life Sciences continues to expand its ELISA portfolio. A leading manufacturer of high quality ELISAs, Enzo continues to invest in developing immunoassays with the launch of their new Total PSA (human) ELISA Kit.
 

Digoxigenin-dUTP and Digoxigenin-UTP for labeling nucleic acids

Strengthening their position as leaders in labeling and detection, Enzo Life Sciences now offers Digoxigenin-dUTP and Digoxigenin-UTP, digoxigenin-labeled nucleotides that are suitable for a variety of molecular biology applications.