DDW ARTICLE DATABASE

THIS MONTH'S LIFE SCIENCE MOVIES
Superheroes
SpectraMax i3 Multi-Mode Detection System
See how you can do more with your microplate reader than you ever imagined.
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Waters
Bioanalysis of Oxytocin
Ultrasensitive Quantification Assay for Oxytocin in Human Plasma Using an LC/MS Microfluidics Platform
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A strategic vision for 21st Century drug discovery.

By Dr W Bowen, Dr G Sanders, Dr A Werdich, Dr B Warrington & Dr E Farrant
Delivering therapeutic innovation is more challenging than ever. Despite major scientific breakthroughs and technological advances leading to a greater understanding of the aetiology of diseases, the current approach to creating new small molecule therapeutics remains fundamentally inefficient.
 

Adopting AI is essential for a sustainable pharma industry.

By Prof Jackie Hunter
Advancements in technology, and in particular, developments in artificial intelligence (AI) are revolutionising the way that we live our lives. Up to now, we have used it to help us find the quickest route home or to search the Internet, but we now need to look much further.
 

Translational Chemical Biology: Gap assessment for advancing drug discovery, development and precision medicine

By Dr M Chorghade, Dr M Liebman, Dr G Lushington, Dr S Naylor & Dr R Chaguturu
As yesterday's lead molecule enters today's clinical trial, the standard operating script calls for product developers and clinicians to push away the originating basic scientists, lest their lofty impractical ideals disrupt a delicate balance of strategic compromise.
 

Filling the drug discovery abyss - novel business models to push through the valley of death

By Dr S Prasad, Dr C McOsker, Prof K Chapman & Dr M Foley
Over the past three years, the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have approved around 200 novel drugs for human use.
 

Is the cloud enabling bioinformatics to become the biology solutions domain?

By Dr Paul Denny-Gouldson
For many years we have used the term bioinformatics to describe, well, anything outside cheminformatics in the R&D informatics domain. It has been a ‘catch-all’ term to label informatics tools that handle biologically relevant information.
 

Kinases and drug discovery: protein kinases as a validated drug target.

By Professor Said A. Goueli
The role of protein and lipid kinases in cellular physiology and normal and abnormal growth has been well appreciated and has been the focus of intensive research in both academic arenas and pharmaceutical industries. The payoff for the pharmaceutical industries has been substantial.
 

Automated liquid handler vendor vs third party plastic company.

By Dr John Comley
Users of automated liquid handlers today invariably have a choice – obtain disposable pipette tips from the original instrument vendor or purchase a ‘compatible’ product from a third party plastics manufacturer or lab supplier.
 

IDBS and ChemAxon partnership extends to harness leading biomolecule handling technology

The strategic partnership with ChemAxon has been further strengthened. IDBS is now able to leverage ChemAxon's Biomolecule Toolkit and BioEddie with its flagship E-WorkBook suite.
 

Innova Biosciences introduces Magnetic Conjugation Kit

Innova Biosciences (Innova), have announced the launch of its Magnetic Conjugation Kit, the newest addition to the company’s range of particle conjugation technologies.
 

Enzo Launches New Nanopolymer Immunohistochemistry Detection Reagents

Enzo have introduced a new line of several in situ hybridization (ISH) and immunohistochemistry (IHC) reagents and their complementary blocker/diluents. These products are offered as higher sensitivity and lower background improvements upon their existing product lines
 

Gilson Launches EXTRACTMAN Magnetic Bead Extraction Platform

Gilson EXTRACTMAN, based on Exclusion-based Sample Preparation technology from Salus Technologies, offers a fast and reliable option to isolate proteins with affinity methods using paramagnetic beads, especially in cases of weak protein interactions or protein interactions with short half lives.
 

Bio-Rad Announces CE IVD Marking of Its QX200 Droplet Digital PCR System

Bio-Rad Laboratories today announced CE IVD marking for its QX200 Droplet Digital PCR System, the first digital PCR system with the CE IVD mark for use as an in vitro diagnostic (IVD) in the European Union.
 

Bio-Rad Launches ddPCR CHO and E. coli Kits for Direct Quantification of Residual Host Cell DNA

The new ddPCR CHO Residual DNA Quantification Kit and Residual DNA Quantification Kit allow for direct quantification of host-cell DNA impurities in biopharmaceuticals purified from bacteria (E. coli) or mammalian cells without the need for upfront nucleic acid purification steps. The kits are designed for use with Bio-Rad’s Droplet Digital™ PCR Systems.