Drug Discovery World, Drug Discovery and Development News

The repositioning revolution: save me from extinction to find me pastures new

By Dr M Green and Dr K Hudson-Farmer

Cost containment and improving ways of treating people are key drivers for healthcare systems. Unfortunately, these do not often go hand in hand. Finding novel therapeutics with enhanced efficacy is both time consuming and costly.

Exploring the feasibility of human antimicrobial peptides for new and more efficient antibiotics

By Dr Max Ryadnov

To help combat decades of stagnation in antibiotic development, a team led by the National Physical Laboratory conducted two studies into the antimicrobial peptides that fight infection in our bodies and the feasibility of using them as the basis for new antibiotic treatment which is less prone to bacterial resistance.

Informatics: the same old problems, just bigger

By Glyn Williams and Dr Paul Denny-Gouldson

Todayâs information technologies profoundly affect the way we conduct research and development (R&D), and the last 20 years have seen great advances in information technology across both our work and home lives.

Progress made in applying 3D cell culture technologies

By Dr John Comley

3D cell culture has the potential to deliver higher quality culture information that is more representative of tissue morphology and predictive of drug responses in vivo.

Digital PCR and real-time PCR: a time and place for each

By Dr George Karlin-Neumann and Dr Rachel Scott

When it comes to DNA research, scientists often find themselves weighing digital PCR (dPCR) against the more established quantitative real-time PCR (qPCR). Which technique is better to use? The answer is both.

Large-scale expansion of stem cells for therapy and screening

By Dr Y. John Shyu, Dr Katherine E. Strathearn and Dr Richard M. Eglen

Recently, pre-clinical and clinical studies of stem cells in regenerative medicine have demonstrated great promise as treatments for various diseases. Their ability to self-renew and differentiate makes stem cells valuable for both cell therapy and tissue engineering fields, both of which drive the demand for largescale cell expansion.

More than genes and cells: drug discovery in the ECM

By Dr William Bains

Drug discovery in the last few decades has focused on the cellular and genetic mechanisms of disease. This has been very successful in cancer, which is a disease of somatic genetics, and moderately successful elsewhere.

Resetting the course of drug development: stem cell banking in support of drug discovery

By Dr T Novak, Dr U Grieshammer, Dr M Yaffe and Dr S Madore

The discovery by Yamanaka and Thomson in 2007 that human somatic cells can be reprogrammed to a pluripotent state (ie, induced pluripotent stem cells, iPSCs) has revolutionised cell biology.

Rigaku Launches New X-Ray Microscope at ACMM23/ICONN2014

February 17, 2014

Rigaku is pleased to announce the release of the nano3DX X-ray microscope, which debuted at ACMM23 & ICONN2014 (the 23rd Australian Conference on Microscopy and Microanalysis and the International Conference on Nanoscience and Nanotechnology).

BioDot has Developed and Launched the BioJet Eliteâ¢ Dispensing Technology

January 2014

BioDot Inc has developed and launched its Biojet Elite dispensing technology.

Fluxion Biosciences expands IsoFlux Discovery Services capabilities with clinical sample procurement

February 2014

New capability provides a full-service option for circulating tumor cell studies

Promega Introduces GloMax Discover Multimode Detection System for Cell and Biochemical Assays

January 2014

New plate reader system provides superior sensitivity, performance, and flexibility with minimal user intervention

New Webinar Compares 2D and 3D Cell Culture Technologies

January 2014

With Data Showing how to Improve Oncology and Toxicology Screening

Waters Introduces UPLC System for nano- to Microscale Separations â the ACQUITY UPLC M-Class System

January 2014

New UPLC System and Columns Drive Separations Efficiency and the Sensitivity of LC-MS Analyses to New Levels

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