Drug Discovery World

Li-SCi MOVIES

This Month’s video

Recent innovations from Labcyte including the newest feature on their Echo liquid handler -Dynamic Fluid Analysis to instantly adapt for changes in fluid properties as each transfer occurs.

A life sciences powerhouse: Ontario, Canada’s story

By Michael Stewart

Around the world, competition between life sciences companies is fierce. And so is the competition between jurisdictions wanting to attract the good paying jobs, innovative spirit and R&D that comes along with this important economic sector.

The Information Symphony: data orchestration for a changing industry managing data on a platform for innovation

By Chris Molloy

A leading ballet conductor recently told me of courses which he runs for senior business leaders.

Current and emerging trends in immunogenicity research

In November 2011 Drug Discovery World hosted a collegial style roundtable discussion on the present and emerging developments in this fundamental area of drug discovery and development. The participants are drawn from the biopharmaceutical, biotechnology and vendor community. This is a transcript of what was discussed in a lively and interesting debate.

Biological analysis and interpretation for improved research outcomes

By Dr Douglas Bassett

In the last few years, technological advancements in the life sciences have changed many ways in which we think about research. Next-generation sequencing, qPCR and microRNA offer new avenues to ask and answer research questions in more detail and in less time.

Stem Cell Banks: investing in the promise of cancer stem cell science

By Madeline Page and Rosario Isasi

The national and international demand for stem cell lines of varying origins (eg human embryonic, induced pluripotent, somatic) and grades (eg research, clinical) is growing.

Optimising well results in label-free analysis

By Dr Stephan Heyse, Dr Oliver Leven and Dr Jon Tupy

Bearing in mind the cost and time required to conduct a screening campaign, it is of paramount importance that screening laboratory scientists process and analyse screen data as carefully and consistently as possible. This paper argues that data analysis software that is modular, process-based and supports visualisation and flexible result generation is essential.

Pathway Analysis: understanding the bridge between environmental cues and cellular response

By Dr John Comley

Understanding the function of a protein in the context of normal and abnormal cellular processes requires a comprehensive knowledge not only of its regulation but also of its role in signalling and metabolic networks in the cell.

Collaborative research leads to new understanding of Biomarkers

By Dr Max Ryadnov and Professor Jason Crain

A new collaborative research paper sheds light on the way antibodies distinguish between different but closely related ‘biomarkers’ – in this case protein fragments which reveal information about the condition of the human body.

From outsourced to open: the continuing evolution of the drug discovery business model

Dr Mary Canady

One doesn’t have to look far to find that the large pharmaceutical business model has many market forces working against it, such as patent expirations, dwindling pipelines, and reduced R&D productivity. However, these factors are driving smaller organisations and individuals to take on small molecule and biological drug development, sometimes with great success.

	Drug Discovery	Business	Chemistry	Enabling Technologies
	Informatics	Personalised Medicine	Screening	Therapeutics

Li-SCi MOVIES

This Month’s video

A life sciences powerhouse: Ontario, Canada’s story

The Information Symphony: data orchestration for a changing industry managing data on a platform for innovation

Current and emerging trends in immunogenicity research

Biological analysis and interpretation for improved research outcomes

Stem Cell Banks: investing in the promise of cancer stem cell science

Optimising well results in label-free analysis

Pathway Analysis: understanding the bridge between environmental cues and cellular response

Collaborative research leads to new understanding of Biomarkers

From outsourced to open: the continuing evolution of the drug discovery business model

ATCC Delivers 350 Different Cell Lines

INDIGO's New Retinoic Acid Receptor Assays

Sygene's New Generation DNA/RNA Safe Dye

Bio-Rad’s New iTaq™ Universal Supermixes

Applications Resource from BMG LABTECH