DDW ARTICLE DATABASE

THIS MONTH'S LIFE SCIENCE MOVIES
Superheroes
SpectraMax i3 Multi-Mode Detection System
See how you can do more with your microplate reader than you ever imagined.
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Waters
Bioanalysis of Oxytocin
Ultrasensitive Quantification Assay for Oxytocin in Human Plasma Using an LC/MS Microfluidics Platform
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LATEST ISSUE:

Digital pharma - responding to challenges and opportunities from outside How digital is reshaping the pharma arena

By Ulrica Sehlstedt, Nils Bohlin, Fredrik de Maré and Richard Beetz
The pharmaceutical industry in the 20th and early 21st century has been in constant change, driven by both incremental and breakthrough innovations.
 

Preclinical imaging: improving translational power in oncology.

By Dr Todd Sasser
Imaging has long been indispensable in clinical practice, and researchers have for many years used the same toolbox of imaging modalities as a component of their preclinical and drug development work.
 

Synthetic lethality and anti cancer drug discovery

By Jonathan D Moore
Classically-activated oncogene targets have been a mainstay of cancer drug discovery for the past 15 years, but the druggable targets in this category have been largely mined out.
 

The coming of age of mass spectrometry imaging.

By Dr Peter J.H. Webborn and Dr Richard J.A. Goodwin
Mapping complex drug distribution/retention in tissues, aligned with efficacy and safety biomarker localisation is now possible using label-free mass spectrometry imaging technologies.
 

Microtissues for in vitro toxicity assessment: Cost effective and in vivo relevant toxicology tools

By Dr Stephanie Ravenscroft, Dr Caroline Bauch, Dr Laura Hinton and Dr Paul Walker
Conventional two-dimensional (2D) cell models (adherent cells grown on cell culture plates or cells in suspension) are limited in their abilities to accurately predict clinical toxicity since they lack the fundamental complexity of in vivo tissue environments.
 

The role of immunodeficient animal models in advancing immuno-oncology research

By Dr Michael Seiler
From inbred wild-type to more advanced genetically-engineered strains, mouse models enable researchers to gain important insights into the complex biological underpinnings of human cancer.
 

The Stem Cell Dilemma: reprogramming in-house versus off-the-shelf purchase of commerciallyproduced iPSC-derived cell types

by Dr John Comley
The case for using more physiologically-relevant cells for modelling disease pathophysiology, for understanding a drug’s mechanism of action, in toxicology/safety testing and in phenotypic drug screening assays is now well accepted.
 




Enzo launches an ultra-sensitive and highly specific Total PSA (human) ELISA Kit

Enzo Life Sciences continues to expand its ELISA portfolio. A leading manufacturer of high quality ELISAs, Enzo continues to invest in developing immunoassays with the launch of their new Total PSA (human) ELISA Kit.
 

Digoxigenin-dUTP and Digoxigenin-UTP for labeling nucleic acids

Strengthening their position as leaders in labeling and detection, Enzo Life Sciences now offers Digoxigenin-dUTP and Digoxigenin-UTP, digoxigenin-labeled nucleotides that are suitable for a variety of molecular biology applications.
 

Innova Biosciences Introduces Thunder-Link PLUS

18 January 2016: Innova Biosciences , specialist provider of bioconjugation products and services, today announced the launch of Thunder-Link® PLUS, a new and improved version of the original Thunder-Link kit.
 

Enzo launches ultra-sensitive highly specific VEGF ELISA Kit

Enzo Life Sciences continues to expand its ELISA portfolio. A leading manufacturer of high quality ELISAs, Enzo continues to invest in developing immunoassays with the launch of their new VEGF ELISA Kit.
 

Enzo Launches EQ Quencher Dyes for Molecular Biology FRET Applications

Enzo Life Sciences now offers EQ Quencher Dyes – amine-reactive quencher dyes that can be used for fluorescence resonance energy transfer (FRET) applications.
 

ImageXpress Micro Confocal High-Content Imaging System Expands the Boundaries of Research

Molecular Devices launches a new confocal technology at the speed of widefield imaging.